A transient parabiosis skin transplantation model in mice
نویسندگان
چکیده
منابع مشابه
Parabiosis in mice: a detailed protocol.
Parabiosis is a surgical union of two organisms allowing sharing of the blood circulation. Attaching the skin of two animals promotes formation of microvasculature at the site of inflammation. Parabiotic partners share their circulating antigens and thus are free of adverse immune reaction. First described by Paul Bert in 1864(1), the parabiosis surgery was refined by Bunster and Meyer in 1933 ...
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Animals in which a transplanted tumor has re gressed usually resist retransplantation of the same tumor; in at least some cases this immunity appears to be tumor-specific (1, 7, 10, 18). Re sistance to retransplantation of tumors has been induced in rats and mice by surgical removal of an established graft (1), tourniquet strangulation of the graft (11), injection of nonliving tumor sub stances...
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Adiponectin is exclusively synthesized by adipocytes and exhibits anti-diabetic, anti-atherosclerotic and anti-inflammatory properties. Hypoadiponectinemia is associated in obese individuals with insulin resistance and atherosclerosis. However, the mechanisms responsible for hypoadiponectinemia remain unclear. Here, we investigated adiponectin movement using hetero parabiosis model of wild type...
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Background: Probiotics are microorganisms that may influence brain function via altering brain neurochemistry. New research evidence suggests that probiotic bacteria might protect tissue damage through diminishing the production of free radicals and/or inflammatory cytokines. Therefore, this study was designed to evaluate the effects of probiotic bacteria on the prevention or reduction of brain...
متن کاملEffects of parabiosis of normal with genetically diabetic mice.
COLEMAN, D. L., AND KATHARINE P. HUMMEL. Effects of parabiosis of normal with genetically diabetic mice. Am. J. Physiol. 2 17(5) : 129% 1304. 1969.-Adult diabetic mice (db/db) of the C57BL/Ks strain were joined in parabiosis with normal mice of the same sex. Little, if any, amelioration of the disease was observed in parabiont diabetics and no symptoms of diabetes were observed in the normal pa...
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ژورنال
عنوان ژورنال: Nature Protocols
سال: 2012
ISSN: 1754-2189,1750-2799
DOI: 10.1038/nprot.2012.032